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If it runs in your family

Family history of bowel cancer

Almost 30% of the UK population has a family history of bowel cancer, so having one is not unusual. What matters is the pattern. Some patterns need referral and colonoscopy surveillance, and for those a stool test is not the right tool. This page tells you which is which, including when we are not what you need.

Reported at 10 µg Hb/g, the symptomatic threshold
Your exact number and a written GP report
A GP consultation included whatever the result
Analysed by The Doctors Laboratory, UKAS No. 9317
The short answer

Family history is not one thing. Guidance sorts it into risk categories, and the category determines whether you need surveillance colonoscopy or not. That distinction matters more than anything else on this page.

If one first degree relative was diagnosed under 50, or two first degree relatives were affected at any age, you meet criteria for at least moderate risk. That means referral and colonoscopic surveillance under BSG, ACPGBI and UKCGG guidance. A stool test is not a substitute for that, and we would rather say so than sell you one.

If your family history is weaker than that, a stool test is a reasonable thing to do. Heritable factors account for roughly 35% of bowel cancer risk, and a family history without an identified syndrome carries a two to sixfold increase over the general population. We report at 10 µg Hb/g and give you the actual number.

When we are not the right answer

Please seek referral rather than ordering a kit if any of these describe your family:

  • One first degree relative (parent, sibling or child) diagnosed with bowel cancer under the age of 50
  • Two or more first degree relatives affected at any age
  • A known inherited syndrome in the family, such as Lynch syndrome or familial adenomatous polyposis
  • A relative found to have a large number of bowel polyps
  • A pattern of several cancers across generations, particularly bowel, womb or ovarian

These patterns are assessed in a familial bowel cancer or genetics clinic, and the answer is usually colonoscopy on a schedule rather than stool testing. Your GP can refer you. We can also discuss it in a consultation, but the destination is the same and we would be doing you a disservice by selling you a kit instead.

What the guidelines say

Five things about family history.

Drawn from the 2020 BSG, ACPGBI and UKCGG hereditary colorectal cancer guideline and NHS genomics guidance.

Almost 30% of the UK population has a family history of bowel cancer.

Which means having one, on its own, is unremarkable. Heritable factors account for roughly 35% of overall bowel cancer risk, but most people with an affected relative do not have an inherited syndrome.

BSG, ACPGBI and UKCGG, Gut 2020

Two patterns change the plan entirely.

One first degree relative diagnosed under 50, or two affected first degree relatives, meets criteria for at least moderate risk. That means referral and colonoscopic surveillance, not periodic stool testing.

A family history without a syndrome carries a two to sixfold increase.

Compared with the general population. Meaningful, and a long way short of the near certainty that inherited syndromes carry. Familial adenomatous polyposis, for comparison, carries a lifetime risk close to 100%.

Surveillance is on a schedule and stool tests are not.

Moderate risk under the guideline means a one off colonoscopy at 55. Higher risk means colonoscopy every five years from 40 to 75. Neither of those is something a home test replaces.

Lynch syndrome is the one worth knowing about.

It is the most common inherited bowel cancer predisposition syndrome, and it is identified through genetic assessment rather than through any stool test. If it is in your family, that is a genetics referral.

Start by working out which group you are in

This is the part most family history pages skip, and it is the only part that changes what you should do.

Your family patternWhat guidance points towards
One first degree relative diagnosed at 50 or over, and no other affected relativesUsually managed as average or low risk: the national screening programme from 50, plus acting on any symptoms
One first degree relative diagnosed under 50At least moderate risk. Referral and colonoscopic surveillance rather than stool testing
Two first degree relatives affected, any ageAt least moderate risk. Referral and colonoscopic surveillance
A known syndrome in the family, many polyps, or several cancers across generationsGenetics referral. Assessment for Lynch syndrome or polyposis, and a surveillance plan built around the finding

First degree means a parent, brother, sister or child. Grandparents, aunts, uncles and cousins are second degree, and they carry less weight in these criteria, though a striking pattern across them is still worth mentioning to a doctor.

Under the 2020 guideline, moderate risk typically means a one off colonoscopy at age 55, with anything found afterwards managed under post polypectomy surveillance rules. Higher risk categories are assessed individually and generally involve colonoscopy every five years from 40 until 75. Those numbers exist because colonoscopy can find and remove polyps before they become anything. A stool test cannot do that, and no amount of testing substitutes for it.

If you meet the criteria for surveillance, take the surveillance. This test is not a cheaper version of a colonoscopy and it would be dishonest to imply otherwise.

Where a stool test genuinely fits

Most people with a family history do not meet those criteria. One relative diagnosed in their late sixties is a common situation and it is not, on its own, a route into a surveillance programme. If that is you, and you are outside the screening age range or between screening rounds, a stool test at the symptomatic threshold is a reasonable thing to do.

Two situations where it is particularly useful:

What a raised result would mean in your situation

The same thing it means for anyone else, with one addition. The threshold is 10 µg Hb/g regardless of family history, because the test measures blood and blood is blood. What family history changes is the prior probability that a given amount of blood reflects something significant, and therefore how quickly and how thoroughly it should be chased.

That is the argument for having a doctor read your result rather than a website. A figure of 24 in someone with no family history and no symptoms is a different conversation from a figure of 24 in someone whose mother was diagnosed at 52, even though the number is identical.

Bring your family history to the consultation

Before your call, try to establish who was affected, what cancer they had, and roughly how old they were at diagnosis. Ages at diagnosis matter more than anything else in these criteria, and they are the detail people most often do not have to hand. Womb and ovarian cancers in the family are worth mentioning too, because they form part of the pattern that prompts a Lynch syndrome assessment.

What we will tell you if you do not need us

If your history meets moderate or high risk criteria, the consultation will tell you to seek referral for colonoscopic surveillance, and we will put that in writing to your GP. That is a worse commercial outcome for us and a better clinical one for you, and there is no version of this where selling a stool test to somebody who needs a colonoscopy is defensible.

The numbers

Four figures from the guideline.

All from the 2020 BSG, ACPGBI and UKCGG hereditary colorectal cancer guideline and NHS genomics guidance.

~30%
of the UK population has a family history of bowel cancer
BSG, ACPGBI and UKCGG, Gut 2020
~35%
of bowel cancer risk is attributable to heritable factors overall
Same guideline
2 to 6x
increased risk in people with a family history but no identified hereditary syndrome
NHS Genomics Education Programme, GeNotes
Under 50
One first degree relative diagnosed under 50, or two affected first degree relatives, meets moderate risk criteria
BSG, ACPGBI and UKCGG surveillance criteria
Being straight with you

Where this test helps, and where it is the wrong tool.

Family history is the topic where the gap between what we sell and what some people need is widest. Here it is plainly.

What this test can do

  • Give you an exact figure between screening rounds, or before screening age begins
  • Be read against 10 µg Hb/g rather than a screening threshold several times higher
  • Give a GP something concrete to interpret alongside your family history
  • Prompt a proper conversation about whether your family pattern warrants referral
  • Be repeated periodically if you are at average risk and outside the screening programme

What it cannot do

  • Replace colonoscopic surveillance if you meet moderate or high risk criteria
  • Find or remove polyps, which is the main reason surveillance colonoscopy exists
  • Diagnose Lynch syndrome, familial adenomatous polyposis or any other inherited condition
  • Rule out bowel cancer. Around 1 in 10 people with colorectal cancer have a result below the threshold
  • Change your risk category. Only assessment of your family history does that
Questions people ask

Family history, answered.

My parent had bowel cancer. What is my risk?

It depends on their age at diagnosis and on how many other relatives were affected. A family history without an identified hereditary syndrome carries roughly a two to sixfold increase over the general population, but the important question is whether you meet criteria for surveillance. One first degree relative diagnosed under 50, or two affected first degree relatives at any age, meets criteria for at least moderate risk under the BSG, ACPGBI and UKCGG guideline. One relative diagnosed at 68 with no other affected relatives usually does not.

Should I get a stool test or a colonoscopy?

If you meet moderate or high risk criteria, colonoscopy on a surveillance schedule, arranged through referral. Moderate risk typically means a one off colonoscopy at 55, and higher risk categories generally involve colonoscopy every five years from 40 to 75. A stool test does not replace that, because surveillance colonoscopy exists to find and remove polyps before they become cancer and no stool test can do that. If your family history does not meet those criteria, a stool test is a reasonable step.

Can a FIT test detect Lynch syndrome?

No. Lynch syndrome is the most common inherited bowel cancer predisposition syndrome and it is identified through genetic assessment, not through any stool test. If there is a known syndrome in your family, or a pattern of bowel, womb and ovarian cancers across generations, that is a genetics referral. Your GP can arrange it.

Does a family history mean I should be screened earlier?

Not automatically. NHS screening invites people from 50 in England, Scotland and Wales and from 60 in Northern Ireland, and a family history does not by itself bring that forward. What does change things is meeting the moderate or high risk criteria, which lead to a separate surveillance pathway rather than to earlier screening. If you are under 50 with a family history that does not meet those criteria, you fall in a gap, and that is the situation this test is genuinely useful for.

Which relatives count?

First degree relatives, meaning parents, brothers, sisters and children, carry the weight in these criteria. Grandparents, aunts, uncles, nieces, nephews and half siblings are second degree and count for less on their own. That said, an unusual pattern across the wider family, or several related cancers across generations, is still worth raising with a doctor because it can point towards a syndrome that the simple criteria miss.

What if I do not know my family history?

That is very common, particularly where relatives died young, records are incomplete, or you are adopted. Bring what you have. Ages at diagnosis matter most, then which cancer it was, then how closely related the person was. Where the history genuinely cannot be established, that uncertainty is itself a reason to have a conversation with a doctor rather than to make an assumption in either direction.

Sources
  1. Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology, the Association of Coloproctology of Great Britain and Ireland and the United Kingdom Cancer Genetics Group. Gut 2020;69:411 to 444.
  2. NHS Genomics Education Programme. GeNotes: patient with a family history of bowel cancer, and patient with a family history of gastrointestinal cancer.
  3. NHS Genomics Education Programme and BSG, ACPGBI and UKCGG 2020 guideline. Lynch syndrome is the most common hereditary bowel cancer predisposition syndrome. Familial adenomatous polyposis carries a lifetime risk close to 100 per cent.
  4. NICE. Quantitative faecal immunochemical testing to guide colorectal cancer pathway referral in primary care. Diagnostics guidance DG56, August 2023.
  5. NICE. Suspected cancer: recognition and referral. NICE guideline NG12, recommendations organised by site of cancer, lower gastrointestinal tract, updated 2023.
  6. UK National Screening Committee. More sensitive bowel cancer screening test implemented in line with UK NSC recommendation. National Screening blog, 26 January 2026.
  7. Cancer Research UK. Quality improvement and future optimisation of bowel screening. Health professional resource.
  8. Faecal immunochemical test to triage patients with possible colorectal cancer symptoms: meta-analysis. British Journal of Surgery 2022;109(2):znab411. Fifteen prospective cohort studies, 28,832 symptomatic patients.

Figures are drawn from the sources above. Framing and commentary are the author’s own. Written and reviewed by Dr Rhea Bhadresha, GP. Last reviewed August 2026.

This page is general information about a test, not personal medical advice. If something about your own health is worrying you, please speak to a doctor.

Know your number, and know your category.

A consultation is included with every test. If your family history means you need surveillance rather than a stool test, we will tell you that and write to your GP.

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